software metabo analyst 4.0 Search Results


99
Shimadzu Corporation nexera uhplc system
Nexera Uhplc System, supplied by Shimadzu Corporation, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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High Fat Diet, supplied by ssniff Spezialdiaten, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Santa Cruz Biotechnology proliferative metabolism
Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and <t>proliferative</t> <t>metabolism</t> (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.
Proliferative Metabolism, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cambridge Isotope Laboratories 13c [1-13c] pyruvic acid
Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and <t>proliferative</t> <t>metabolism</t> (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.
13c [1 13c] Pyruvic Acid, supplied by Cambridge Isotope Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ICN Biomedicals 40 mci/ml of [35s]cys/met mixture
Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and <t>proliferative</t> <t>metabolism</t> (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.
40 Mci/Ml Of [35s]Cys/Met Mixture, supplied by ICN Biomedicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thermo Fisher c_30634242_40
Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and <t>proliferative</t> <t>metabolism</t> (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.
C 30634242 40, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ICN Biomedicals 0.5% nonidet p-40
Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and <t>proliferative</t> <t>metabolism</t> (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.
0.5% Nonidet P 40, supplied by ICN Biomedicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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c33  (ATCC)
96
ATCC c33
Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and <t>proliferative</t> <t>metabolism</t> (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.
C33, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thermo Fisher dextran coated charcoal 2 p r endocrinology 274 2007 19 29 dcc stripped fbs
Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and <t>proliferative</t> <t>metabolism</t> (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.
Dextran Coated Charcoal 2 P R Endocrinology 274 2007 19 29 Dcc Stripped Fbs, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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91
Revvity sodium 1 14 c acetate
Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and <t>proliferative</t> <t>metabolism</t> (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.
Sodium 1 14 C Acetate, supplied by Revvity, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Gilead Sciences admet descriptors
Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and <t>proliferative</t> <t>metabolism</t> (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.
Admet Descriptors, supplied by Gilead Sciences, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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SUZUKEN CO LTD portable metabolic rate monitor
Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and <t>proliferative</t> <t>metabolism</t> (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.
Portable Metabolic Rate Monitor, supplied by SUZUKEN CO LTD, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and proliferative metabolism (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.

Journal: International Journal of Molecular Sciences

Article Title: Normoxic Tumour Extracellular Vesicles Modulate the Response of Hypoxic Cancer and Stromal Cells to Doxorubicin In Vitro

doi: 10.3390/ijms21175951

Figure Lengend Snippet: Overview on the molecular changes related to the resistance inducing mechanisms in C26 cells to DOX treatment under normoxia. Cropped Western blot images and their representative graphs displaying the percentage of protein levels after 24 h treatment with 0.3 µM DOX under normoxia compared to controls (the levels of the same proteins in untreated cell lysates) are shown for phosphatidylinositol-3 kinase (PI3K) in panel ( A ); for protein kinase B (Akt) in panel ( B ); for proto-oncogene tyrosine-protein kinase Src (c-Src) in panel ( C ); for the c-Jun subunit of AP-1 transcription factor (AP-1 c-Jun) in panel ( D ); for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65) in panel ( E ); for c-master regulator of cell cycle entry and proliferative metabolism (c-Myc) in panel ( F ); for B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL) in panel ( G ), for Bcl-2-associated X protein (BAX) in panel ( H ); and for hypoxia-inducible factor 1-alpha (HIF-1α) in panel ( I ). β-actin was used as loading control. Data were expressed mean ± SD of duplicate measurements from two independent experiments. Unpaired t -test was used for statistical analysis of the data; ns : not significant, p > 0.05; *, p < 0.05; **, p < 0.01, ***, p < 0.001.

Article Snippet: Membranes were incubated with primary antibodies overnight at 4 °C for p65 subunit of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB p65; mouse monoclonal IgG anti-mouse, 1:500 dilution, sc-56735, Santa Cruz Biotechnology, Santa Cruz, CA, USA), c-Jun subunit of activator protein 1 (AP-1 c-Jun; rabbit polyclonal IgG anti-mouse, 1:1000 dilution, sc-45, Santa Cruz Biotechnology), B-cell lymphoma–extra-large anti-apoptotic protein (Bcl-xL; rabbit monoclonal IgG anti-mouse, 1:500 dilution, 2764, Cell Signaling), phosphatidylinositol-3 kinase (PI3K; rabbit polyclonal IgG anti-mouse, 1:1000 dilution, 4292, Cell Signaling, Beverly, MA, USA), protein kinase B (Akt; rabbit monoclonal IgG anti-mouse, 1:1000 dilution, 4691, Cell Signaling), proto-oncogene tyrosine-protein kinase Src (c-Src; rabbit polyclonal IgG anti-mouse, 1:1000 dilution, sc-018, Santa Cruz Biotechnology), c-master regulator of cell cycle entry and proliferative metabolism (c-Myc; mouse monoclonal IgG anti-mouse, 1:500 dilution, sc-42, Santa Cruz Biotechnology), Bcl-2-associated X protein (BAX; rabbit polyclonal IgG anti-mouse, 1:500 dilution, 2772S, Cell Signalling), hypoxia-inducible factor 1-alpha (HIF-1α; rabbit polyclonal IgG anti-mouse, 1:500 dilution, ab17983, Abcam, Newcastle, UK), β-actin (rabbit polyclonal IgG anti-mouse, 1:1000 dilution, sc-130656, Santa Cruz Biotechnology), and HRP-labeled IgG goat anti-rabbit (sc-2004) or goat anti-mouse (sc-2005) secondary antibodies (1 h incubation, 1:2500 dilution, Santa Cruz Biotechnology).

Techniques: Western Blot, Control